OUR TECHNOLOGY

CRISPR – The future of diagnostics is here

Recently devised CRISPR-technologies represent the unprecedented opportunity to reshape epidemiological surveillance and molecular diagnostics. CRISPR-based diagnostic tools promises to dramatically transform molecular diagnostics, making them easily affordable and accessible virtually anywhere in the world.

The identification of a pathogen nucleic acid can be performed in 3 simple steps

How CRISPR works

First, a sample of the patient's bodily fluid, such as blood or saliva, is collected. Next, CRISPR reagents that are designed specifically for each disease are added to the sample and analyzed for the presence of the disease-causing agent. The signal released by our reporters can be detected by lateral flow strips or fluorescence within our Vivaldi instrument. Finally, the test results are reported to the healthcare provider or the patient. The time required to complete this process is about 30 minutes.

Ultimately, those steps can be combined as one-pot rapid diagnostic technology.

Why CRISPR?

CRISPR-based diagnostics offer several advantages over traditional diagnostic methods, including greater speed, sensitivity, and specificity. They also have the potential to be more affordable and accessible, making them an important tool for disease surveillance and outbreak control.

CRISPR – Main Advantages

In the presence of the pathogen nucleic acid, gRNA/Cas complex will bind and cleave the amplified fragments, being capable of detecting a single molecule in 1μl sample volumes
Some readout strategies are fast and low-cost, suitable for POC or field applications.
The usage of reporter molecules with different properties enables a wide variety of readouts, including fluorescence and lateral-flow strips.
Most CRISPR-based diagnostic tools can be performed in less than one hour, and the required reagents are inexpensive.
Because Cas proteins bind to target DNA or RNA in a sequence-specific manner, searching for a new target gene of interest can be done by simply changing the sequence of gRNA, without any protein engineering or complex optimization of the experimental condition.

Nucleic Acid Detection by CRISPR

Designed with accuracy and simplicity in mind

Our research and development efforts are focused on addressing the needs of patients by targeting specific diseases, with the aim of advancing diagnostic technologies and treatment options to improve patient care and quality of life.

OUR TECHNOLOGY

CRISPR – The future of diagnostics is here

The identification of a pathogen nucleic acid can be performed in 3 simple steps

How CRISPR works

Ultimately, those steps can be combined as one-pot rapid diagnostic technology.

Why CRISPR?

CRISPR-based diagnostics offer several advantages over traditional diagnostic methods, including greater speed, sensitivity, and specificity. They also have the potential to be more affordable and accessible, making them an important tool for disease surveillance and outbreak control.

CRISPR – Main Advantages

Nucleic Acid Detection by CRISPR

Designed with accuracy and simplicity in mind

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